Major Depressive Disorder Treatment

Neuro-MS/D Transcranial Magnetic Stimulator

  • Effective treatment of Major Depressive Disorder
  • High-performance machine for intensive use
  • Advanced liquid cooling technology
  • Angulated figure-of-eight coil for precise stimulation of dorsolateral prefrontal cortex
  • 3-minute depression treatment protocol
Major Depressive Disorder Treatment


Effective treatment of Major Depressive Disorder

Nowadays, both pharmacological and non-pharmacological options are used to treat the depression. Most often a patient is offered either pharmacological or the combined treatment consisting of antidepressant medication and psychotherapy, which really works, but, unfortunately, not for everyone. If the patient does not respond to medication or can not tolerate the side effects of medication, rTMS therapy becomes an alternative. Magnetic stimulators can perform stimulation of dorsal prefrontal cortex (DLPFC). It impacts the mood stabilizers, thus, the long-lasting therapeutic effect, non-invasive, with no pain and minimum contraindications is achieved. According to the results of the clinical trials, the number of responders to rTMS therapy in antidepressant treatment-resistant patients is about 50%. At that, depending on the depression type the remission is reached in every second* patient. The Neuro-MS/D configurations are not only highly effective but also thoughtfully-designed. Neurosoft magnetic stimulators are the obvious choice of TMS specialists all over the world. The choice of those, who values reliability, safety and time.

Advanced liquid cooling technology

The cooling system is designed to avoid the coil overheating during long-term rTMS sessions. The advanced method of active coil component cooling is implemented in Neurosoft magnetic stimulators. The cooling liquid does not fill the whole coil, is runs inside the winding. This liquid does not increase the weight of coil and neutralizes the heat on-site.

Angulated figure-of-eight coil for precise stimulation of dorsolateral prefrontal cortex

The accurate focused stimulation of dorsal prefrontal cortex is ensured with angulated figure-of-eight coil. The anatomic coil shape that is congruent to head shape allows achieving the precision in positioning TMS coil and avoiding coil dislocation
from stimulation point.

3-minute depression treatment protocol

Now the Neuro-MS.NET is equipped by new short depression treatment protocol.
In accordance with the clinical tests performed by leading research hospitals in Canada*, in patients with treatment-resistant depression, iTBS was non-inferior to 10 Hz rTMS for the treatment of depression. Both treatments had low numbers of dropouts and similar side-effects, safety, and tolerability profiles. By use of iTBS, the number of patients treated per day with current rTMS devices can be increased several times without compromising clinical effectiveness.
So the 3-minute treatment is as safe and effective for the depression treatment as the conventional TMS.

Advanced software with automatic tools and preset treatment protocols

When you purchase Neuro-MS/D magnetic stimulator, you get the advanced software with the set of predefined protocols implemented in accordance with IFCN** recommendations. These protocols can be used to treat psychiatric and neurological diseases. The well-laid-out software features streamline TMS workflow and save considerably the time.

*Carpenter L et al. Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of acute treatment outcomes in clinical practice. Depression and Anxiety 2012; 29: 587-596.
** Lefaucheur J-P et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). Clin Neurophysiol (2014). Depending on local regulations in different countries some protocols can be disabled.
*** Blumberger D. M. et al. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial //The Lancet. – 2018. – Т. 391. – №. 10131. – С. 1683-1692.

For North America USA customers please visit this page.

Delivery Set

The delivery set can differ from country to country. Request the actual delivery set for your country from your local representative.

Neuro-MS/D main unit1 pcs.
Neuro-MS/D cooling unit1 pcs.
Neuro-MS/D extra power supply unit1 pcs.
End cap1 pcs.
Patient cap , size 42-5410 pcs.
Patient cap , size 54-6610 pcs.
Silicone oil , canister, 3 l1 pcs.
AFEC-02-100-C cooled angulated figure-of-eight coil, 100 mm1 pcs.
Hydraulic system adapter2 pcs.
Control cable for Neuro-MS/D cooling unit1 pcs.
HV cable for extra power supply unit connection to Neuro-MS/D1 pcs.
Equipotential cable2 pcs.
Monitor-computer cable , 220 V, 1.8 m, 3х0.751 pcs.
SCZ-1 mains supply cable2 pcs.
USB cable , A-B1 pcs.
K-3 flexible arm for coil positioning1 pcs.
К-8 coil holder , trolley/wall mounted1 pcs.
T-4/A trolley1 pcs.
NS4D 42006 3/8" quick connect coupling1 pcs.
Technical Manual "Neuro-MS/D"1 pcs.
Warranty certificate1 pcs.
Technical Manual «Coils for Magnetic Stimulators»1 pcs.
User manual «Neuro-MS.NET », ver.21 pcs.
''Transcranial Magnetic Stimulation'' handbook by Moacyr Alexandro Rosa and Marina Odebrecht Rosa1 pcs.
Package2 pcs.
Package1 pcs.
Screwdriver1 pcs.
License for Neuro-MS.NET software1 pcs.


Neurosoft beats the competition in many ways, including ease of use, great interface, and equipped with software containing automated protocols. The team is outstanding with personalized service!
As a psychiatrist who does a lot of TMS treatments, I was interested when I found out that the NeuroSoft TMS system was FDA cleared. When I looked into it I found that it was the NeuroSoft TMS system which I was first introduced to in Singapore in 2015. I saw it demonstrated at every conference since that time but I did not appreciate it until I considered purchasing the system. The price is the most obvious attractive feature. It is not only about $10,000 less then the nearest competitor, but its performance matches and even exceeds some of the other TMS systems currently on the market. When my unit arrived and Fred showed me how it worked I was amazed at how simple it was. We can train our technicians on this machine in about a minute. The movement of the coil holder is smooth and fluid. This system runs very cool even when treatments are back to back for several hours. We have had no problem overheating. This NeuroSoft TMS system is a superb choice. We have seen equal results with it and have no complaints from patients or technicians. I can recommend this system highly.


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